Nicholas DUNNE
Prof. Nicholas Dunne holds a degree in Polymer Science from the Technological University Shannon and a PhD from Queen’s University of Belfast (QUB). He is a Full Professor of Biomaterials Engineering and Chair of Mechanical and Manufacturing Engineering at Dublin City University (DCU), where he serves as the Founding Executive Director of Biodesign Europe and the Executive Director of the Centre for Medical Engineering Research. Additionally, he holds honorary and adjunct professorships at QUB and Trinity College Dublin.
Internationally, recognised for his expertise in biomaterials for tissue repair and regeneration, Prof. Dunne has received prestigious awards and fellowships from the Orthopaedic Research Society-British Orthopaedic Research Society, and the Royal Academy of Engineering-Leverhulme Trust. Additionally, he has been inducted into the International College of Fellows of Biomaterials Science and Engineering. His research attracts substantial funding from national and international sources, having secured over €43 million as a principal and co-investigator.
Prof. Dunne is the author of over 250 peer-reviewed journal articles and has approx. 460 contributions to international scientific meetings. He serves as Journal Editor of Biomaterials Advances and Editorial Board Member of Regenerative Biomaterials, RSC Biomaterials Science, Joxurnal of Materials Science: Materials in Medicine and Proceedings of IMechE, Part H: Journal of Engineering in Medicine.
Passionate about engaging early career researchers, Prof. Dunne has held leadership positions as President of the Northern Ireland Bioengineering Society (2008-2015) YSF-ESB Spokesperson (2010-2014) and UKSB (2011-2015). He was the Vice President and Secretary of the Executive Organising Committee of the 11th WBC (Glasgow, 2020) and an Executive Organising Committee member of the 8th WCB (Dublin, 2018). He is currently the President of the European Society for Biomaterials, having previously served as its Council Secretary.
Abstract
Innovations in Tissue Repair: Interdisciplinary Strategies for Biomaterial-Assisted Targeted Delivery and Scalable Synthesis
Although hard and soft tissues possess an intrinsic capacity for repair, there are certain cases where healing is either impaired or insufficient, such as non-union fractures, osteoporosis, diabetic foot and pressure ulcers, epidermolysis bullosa, and cancers. In these cases, current treatments like surgical interventions are used, either alone or in combination with bioactive agents, to promote tissue repair and manage associated clinical complications. To enhance the effectiveness of bioactive agents, carriers, particularly biomaterials, play a pivotal role. In this talk, we will discuss the importance of adopting an interdisciplinary approach to realise targeted delivery of bioactive agents to tissues. Importantly, this talk will explore the application of biomaterials and non-viral vector delivery systems, emphasizing their role in overcoming challenges associated with impaired or insufficient tissue repair. Further, it will extend to the synthesis routes of these biomaterial-assisted target therapies, highlighting their scalability for large-scale manufacture. The talk will also touch upon the application of data analytics to accelerate development, offering practical insights into translating research findings into clinical applications. This comprehensive discussion aims to showcase recent advancements from the Dunne lab and foster collaboration in the dynamic field of biomaterial-assisted targeted delivery for tissue repair.
BiomMedD' 2024
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